What are the disadvantages of cisplatin?

Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia, and/or bleeding.

1. What are the long-term side effects of cisplatin?
2. Can cisplatin cause permanent damage?
3. Is cisplatin a strong chemo?
4. How long can I use cisplatin?
5. When do cisplatin side effects start?
6. Does cisplatin affect the kidneys?
7. What are the signs that chemo is working?
8. How many rounds of chemo is normal?
9. Does cisplatin cause other cancers?
10. Which chemo has the worst side effects?
11. What cancers are treated with cisplatin?
12. Will I lose my hair with cisplatin?
13. Can cisplatin cause heart problems?
14. What drug is given with cisplatin?
15. What is the strength of cisplatin injection?

What are the long-term side effects of cisplatin?

One of the most common long-term side effects of Platinol (cisplatin), a medication used for many cancers including lung cancer, is hearing loss (ototoxicity). Other medications may also cause hearing loss and tinnitus (ringing in the ears).

Can cisplatin cause permanent damage?

Cisplatin (CDDP) is a frequently employed chemotherapeutic drug both in curative and palliative settings. When cancer patients are cured due to CDDP therapy, they unfortunately often experience severe long‐term side effects including irreversible hearing loss (ototoxicity) and permanent neuronal and renal damage.

Is cisplatin a strong chemo?

Presently, cisplatin is one of the most powerful chemotherapeutic drugs used for the treatment of ovarian cancer; even though resistance is typical [20]. In ovarian germ cell cancer, the use of cisplatin brings about high response rates [21].

How long can I use cisplatin?

Your course of chemotherapy

You have chemotherapy as a course of several sessions (or cycles) of treatment over a few months. Each cycle of cisplatin usually takes 21 days (3 weeks). You usually have the cisplatin on the first day of each cycle. But this will depend on the type of cancer you have.

When do cisplatin side effects start?

Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours. Various degrees of vomiting, nausea and/or anorexia may persist for up to 1 week after treatment.

Does cisplatin affect the kidneys?

In addition, cisplatin may cause renal vasoconstriction through injury on the renal vasculature, which reduces blood flow, causing ischemic damage to the kidney and affects the glomerular filtration rate. Finally, a series of adverse reactions trigger acute renal failure.

What are the signs that chemo is working?

Complete response - all of the cancer or tumor disappears; there is no evidence of disease. A tumor marker (if applicable) may fall within the normal range. Partial response - the cancer has shrunk by a percentage but disease remains. A tumor marker (if applicable) may have fallen but evidence of disease remains.

How many rounds of chemo is normal?

During a course of treatment, you usually have around 4 to 8 cycles of treatment. A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover.

Does cisplatin cause other cancers?

Background. Case reports, retrospective analyses, and observational studies have linked the use of cisplatin to increased risk of second cancers, especially life-threatening secondary leukemia.

Which chemo has the worst side effects?

Integumentary system (skin, hair, and nails) Hair loss is perhaps the most infamous side effect of chemo treatments.

What cancers are treated with cisplatin?

Cisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar platinum-based drugs were developed with National Cancer Institute (NCI) support.

Will I lose my hair with cisplatin?

v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment.

Can cisplatin cause heart problems?

Cisplatin chemotherapy is also associated with cardiotoxic effects that may range from silent arrhythmias to heart failure and even sudden cardiac death. These effects are more pronounced when cisplatin is combined with other cardiotoxic drugs.

What drug is given with cisplatin?

Droperidol 1 mg was given intramuscularly (IM) 15 minutes prior to beginning cisplatin. Repetitive doses of intravenous (IV) metoclopramide, 2 mg/kg in 75 ml 5% dextrose in water over 15 minutes was given 30 minutes prior to, and at 1 1/2, 4 1/2, and 7 1/2 hours after beginning cisplatin chemotherapy.

What is the strength of cisplatin injection?

Cisplatin Injection, 1 mg/mL, is supplied in multiple dose vials containing 50 mL and 100 mL.